Osteoporosis Treatment Drugs, Medications and Side Effects

Currently, several drugs have been approved for treatment and prevention of osteoporosis.

Bisphosphonates
Bisphosphonates slow bone loss and reduce fracture risk by decreasing bone-dissolving cell activity. And for some it also increases their bone density. Examples of this class of drugs are:

  • alendronate
  • risedronate
  • ibandronate
  • zoledronic acid

Some side effects you may experience while taking bisphosphonates orally include:

Some side effects you may experience while taking bisphosphonates intravenously include:

Reportedly, these symptoms typically subside within a couple of days.

Raloxifene
Reloxifene is used for postmenopausal women. It is a nonhormonal drug that has an estrogen-like effect by slowing bone loss and reducing fracture risk in your spine. However, no effect on hip fractures has been documented. Side effects may include:

Calcitonin
Calcitonin is used as a daily nasal spray or injection by women who are at least 5 years post menopause. It is a thyroid producing hormone that slows bone loss and reduces the risk of spine fractures. This drug treatment has no reported serious side effects.

Teriparatide
Teriparatide is a type of human parathyroid hormone that stimulates new bone formation. It increases bone tissue and bone strength, and has been shown to reduce the risk fractures. Some experience:

Estrogen
Estrogen is used for the treatment of menopausal symptoms and osteoporosis. And the lowest effective dose for the shortest period should only be considered for those with a significant risk of osteoporosis. Recent evidence indicates that taking estrogen increases the risk of:

Therefore, other nonestrogen medications should be considered first.

Presently, additional treatments for bone health are being explored, such as:

Also, genetics and environment roles in the development of osteoporosis are being analyzed.